new deadly human-to-human-transmissible coronavirus emerges out of China
POSTED BY: 1KIKI
UPDATED: Tuesday, May 5, 2026 22:21
VIEWED: 203741
PAGE 279 of 283
I guess I missed the Anniversary celebration of this thread.
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Quote:
Originally posted by SIGNYM:
Hubby had an interesting theory about how Omicron might displace other variants without involving the immune system: what if Omicron literally occupies all of the ACE receptors and doesn't leave room for any other variant? So they literally starve to death, in a sense bc they can't find any host cells?
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Pity would be no more,
If we did not MAKE men poor - William Blake
I'd have to think about the biology some (is it the ACE-2 receptor in the lungs or in the upper airways where infection first takes place?), but ... yeah, that could be.
Anyway, another question I'd have is if the Omicron variant is competitive or non-competitive with Delta for an attachment site.
The are 2 different kinds of attachment in the very generic sense - competitive and non-competitive.
Of the non-competitive type, one common example is carbon monoxide and how it sticks to hemoglobin. Carbon monoxide attaches to hemoglobin roughly 400X more strongly than oxygen does. To all intents and purposes, the CO is never coming off the hemoglobin, it's permanently stuck there until the hemoglobin gets destroyed. So anything else - like oxygen - can no longer attach to hemoglobin. And that's how people with carbon monoxide poisoning can die - their hemoglobin is too full-up with carbon monoxide and can no longer carry enough oxygen to their body (at ordinary concentrations and pressures. That's why ppl with carbon monoxide poisoning are sometimes treated in hyperbaric chambers.).
Carbon monoxide is a non-competitive inhibitor of oxygen.
Then there's competitive inhibition, where the 2 chemicals actively jostle each other on and off an attachment place. (I can't think of a common example.)
If Omicron is in essence a non-competitive inhibitor of Delta, that would make it even more effective as a Delta blocking agent.
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Quote:I'm all about going to original data. First of all the link provided from Jack's story isn't an up-to-date one. But hey, if I couldn't find the real link, that would be pretty pathetic.
Originally posted by SIGNYM:
A lot of ppl delayed getting tested or seeing a doctor until after vaccination.
It would be interesting to see if there was a DROP in cancer diagnosis in 2019-2020 as pl stayed away from doctor's offices, clinics, and screening tests. They do expect to see that in the general population altho the data isn't out yet.
I read the link, they ruled that out for miscarriages but didn't detail the other dxs.
And what about conditions Not expected to be associated with vaccines?
Did they go up too? Stay the same? Go down? You need some sort of internal control to understand the data.
Because if you're looking for something and filtering the data, you might find an artefact of your process, not the real deal.
So, interesting but I would like to see the data.
The truth is out there. You just need to find it.
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Pity would be no more,
If we did not MAKE men poor - William Blake
But at the real link, sadly, I'm not and will not become an 'authorized user'. Well, darn. So much for an interesting traipse through the numbers.
I agree, Signy. Without more information, the story is uninterpretable.
I also question the time period of their baseline, btw. That's another thing that could easily mask the facts.
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Sorry you are ill, Signy. Hope the chemo does the trick and you get through it as well as can be expected. I can understand why you are laying low.
My own covid experience, seeing as though anecdotal appears to mean something here. Son got COVID on new years eve, same as everyone who partied on that night. He tested postive and I tested negative. He is twice vaxed with pfizer and I was twice vaxed with AZ. When he was just started to be symptomatic, I got myself the booster, not quite ethical as I was pretty sure he had it but I double masked and was in and out in a flash. I knew that AZ was not effective against omicron, particularly as time goes on.
Son got it mildly, a summer cold, with a residual cough afterwards. We kept our distance in the house and I didn't develop any symptoms. It's an interesting one. Summer here, easy to keep the air circulating and be outside most of the time, but not sure that booster would have worked its magic in that timeframe.
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We can't believe anything that isn't printed by the Legacy Media without heavy scrutiny.
Anything that is published by the Legacy Media though, we just buy those numbers.
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Vaccinated People: "You need to get muh vaccination shots that don't work because I got muh vaccination shots that don't work and I'm afraid of people that didn't get muh vaccination shots that don't work because muh vaccination shots that don't work don't work."
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Quote:
Originally posted by Magonsdaughter:
Sorry you are ill, Signy. Hope the chemo does the trick and you get through it as well as can be expected. I can understand why you are laying low.
My own covid experience, seeing as though anecdotal appears to mean something here. Son got COVID on new years eve, same as everyone who partied on that night. He tested postive and I tested negative. He is twice vaxed with pfizer and I was twice vaxed with AZ. When he was just started to be symptomatic, I got myself the booster, not quite ethical as I was pretty sure he had it but I double masked and was in and out in a flash. I knew that AZ was not effective against omicron, particularly as time goes on.
Son got it mildly, a summer cold, with a residual cough afterwards. We kept our distance in the house and I didn't develop any symptoms. It's an interesting one. Summer here, easy to keep the air circulating and be outside most of the time, but not sure that booster would have worked its magic in that timeframe.
This sounds like any joke I've heard about Branch Covidians.
You seriously double masked?
Good for you. I think that's the key to finally getting over this. Everyone who is afraid can just wear two masks for the rest of their lives and the rest of the world can just go on living.
--------------------------------------------------
Vaccinated People: "You need to get muh vaccination shots that don't work because I got muh vaccination shots that don't work and I'm afraid of people that didn't get muh vaccination shots that don't work because muh vaccination shots that don't work don't work."
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Quote:
Originally posted by SIGNYM:
A lot of ppl delayed getting tested or seeing a doctor until after vaccination.
It would be interesting to see if there was a DROP in cancer diagnosis in 2019-2020 as pl stayed away from doctor's offices, clinics, and screening tests. They do expect to see that in the general population altho the data isn't out yet.
I read the link, they ruled that out for miscarriages but didn't detail the other dxs.
And what about conditions Not expected to be associated with vaccines?
Did they go up too? Stay the same? Go down? You need some sort of internal control to understand the data.
Because if you're looking for something and filtering the data, you might find an artifact of your process, not the real deal.
So, interesting but I would like to see the data.
The truth is out there. You just need to find it.
-----------
Pity would be no more,
If we did not MAKE men poor - William Blake
Quote:
Originally posted by 1KIKI:
I'm all about going to original data. First of all the link provided from Jack's story isn't an up-to-date one. But hey, if I couldn't find the real link, that would be pretty pathetic.
But at the real link, sadly, I'm not and will not become an 'authorized user'. Well, darn. So much for an interesting traipse through the numbers.
I agree, Signy. Without more information, the story is uninterpretable.
I also question the time period of their baseline, btw. That's another thing that could easily mask the facts.
Anyway Signy, I think you make good points, and I wanted to follow up because 2 things caught my eye without even thinking about it:
1) As reported, they restricted their data to outpatients only. Why would they do that? Because if the military health system did what the civilian health system did, ALL non-critical care was made outpatient - to keep inpatient facilities with COVID-19 patients from becoming miasmas where COVID-19 rampantly spreads to everyone who's there for any reason.
If I was looking at the data I'd probably keep inpatient and outpatient data separate - because one doesn't want to lose granularity unless it's non-informative - but also look at the sum of inpatient+outpatient, to literally account for any change in admitting practices.
2) They used a 5-year average. Why would they do that? (Unless maybe it was a handy tool in the database itself and they were being too lazy to do anything else.)
Because my experience when looking at enormous data sets to validate them is that one needs to literally look at it graphically several ways in order to let the data speak. And, as I've read in many statistical books and found by experience, there's no easy way to figure out ahead of time what will make a pattern clearest.
So I would have taken perhaps 10 or even 15 years of data of a sampling of individual diagnoses, graphed them across the years, and looked for patterns ... like high variability year to year, or overall low levels with occasional random spikes. Unless you know what 'normal' data looks like, you can't set such narrow parameters and then conclude something is 'different'.
Also, when it comes to validating large data sets one needs to look for internal validation of data (for example flu deaths can never exceed flu diagnoses), as well as statistical correlations. (BTW this also goes for validating votes, which, except for Mitofsky refuting the validity of Bush vote data, has never been done.)
I've looked at too many original cooked 'research' papers - the latest example was the study in Brazil involving tens of thousands of people that 'proved' ivermectin worked that was so deeply flawed it was invalid - to automatically trust anyone who claims to have data on their side. And, by the reporting on this one, there are too many questions I'd need to see answered before I thought the results were meaningful.
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Quote:
Originally posted by 6IXSTRINGJACK:Quote:
Originally posted by Magonsdaughter:
Sorry you are ill, Signy. Hope the chemo does the trick and you get through it as well as can be expected. I can understand why you are laying low.
My own covid experience, seeing as though anecdotal appears to mean something here. Son got COVID on new years eve, same as everyone who partied on that night. He tested postive and I tested negative. He is twice vaxed with pfizer and I was twice vaxed with AZ. When he was just started to be symptomatic, I got myself the booster, not quite ethical as I was pretty sure he had it but I double masked and was in and out in a flash. I knew that AZ was not effective against omicron, particularly as time goes on.
Son got it mildly, a summer cold, with a residual cough afterwards. We kept our distance in the house and I didn't develop any symptoms. It's an interesting one. Summer here, easy to keep the air circulating and be outside most of the time, but not sure that booster would have worked its magic in that timeframe.
This sounds like any joke I've heard about Branch Covidians.
You seriously double masked?
Good for you. I think that's the key to finally getting over this. Everyone who is afraid can just wear two masks for the rest of their lives and the rest of the world can just go on living.
--------------------------------------------------
Vaccinated People: "You need to get muh vaccination shots that don't work because I got muh vaccination shots that don't work and I'm afraid of people that didn't get muh vaccination shots that don't work because muh vaccination shots that don't work don't work."
Yep, you don't get much do you? Double masking was to protect others when I thought I might have been contagious. People who are vulnerable, like Signy.
Interesting to see what has happened here, gone from little COVID to the Omicron spreading like wildfire. The health care system near collapse demonstrating that Omicron still impacts those at high risk and the unvaccinated. If I'm fearful, it's that I or someone may need an ambulance or a hospital bed - non covid related - and won't be able to access them due to the high numbers taking up beds/ ambulances/icu space.
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You live in a pretty scary reality, Mags.
Life must have been terrifying for you the last two years.
You have my pity.
--------------------------------------------------
Vaccinated People: "You need to get muh vaccination shots that don't work because I got muh vaccination shots that don't work and I'm afraid of people that didn't get muh vaccination shots that don't work because muh vaccination shots that don't work don't work."
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Quote:
Study finds Omicron infection effectively induces immunity against itself and enhances protection against other variants in vaccinated individuals
https://www.news-medical.net/news/20220120/Study-finds-Omicron-infecti
on-effectively-induces-immunity-against-itself-and-enhances-protection-against-other-variants-in-vaccinated-individuals.aspx
Study in humanized mice experimentally infected with various strains of Covid finds that
Quote:
Sera from mice infected with Delta had the largest cross-variant neutralization, effectively neutralizing all strains except Beta. While Omicron-infected sera efficiently neutralized Omicron, it only had a minimal cross-neutralization effect on other strains. Sera from WA1-infected mice protected against WA1, Alpha, and Delta, but not against Beta and Omicron. Sera from vaccinated people with confirmed Omicron breakthrough infection, in particular, exhibited the highest level of protection against all strains, including Omicron.
Based on the study findings, while the Omicron variant is immunogenic, infection with this variant in uninfected and unvaccinated individuals may not elicit effective cross-neutralizing antibodies against other variants. However, Omicron infection promotes immunity against itself in vaccinated individuals and improves protection against other variants. This suggests that Omicron- and Delta-based immunogens should be included in future multivalent vaccination regimens to provide widespread protection against all variants.
-----------
Pity would be no more,
If we did not MAKE men poor - William Blake
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