new deadly human-to-human-transmissible coronavirus emerges out of China
POSTED BY: 1KIKI
UPDATED: Tuesday, May 5, 2026 22:21
VIEWED: 203741
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NYTimes
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New deaths 506 +89% deaths trajectory last two weeks
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New deaths 516 +92% deaths trajectory last two weeks
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Quote:OK, this is the first that I've heard that these are both full-length spike protein-encoding vaccines. I had read that sputnik V was, but didn't know that about these
Comparison of two highly-effective mRNA vaccines for COVID-19 during periods of Alpha and Delta variant prevalence
Although clinical trials and real-world studies have affirmed the effectiveness and safety of the FDA-authorized COVID-19 vaccines, reports of breakthrough infections and persistent emergence of new variants highlight the need to vigilantly monitor the effectiveness of these vaccines.
Here we compare the effectiveness of two full-length Spike protein-encoding mRNA vaccines
Quote:MORE HERE https://www.medrxiv.org/content/10.1101/2021.08.06.21261707v1
from Moderna (mRNA-1273) and Pfizer/BioNTech (BNT162b2) in the Mayo Clinic Health System over time from January to July 2021, during which either the Alpha or Delta variant was highly prevalent.... cohorts of vaccinated and unvaccinated individuals from Minnesota (n = 25,589 each) matched on age, sex, race, history of prior SARS-CoV-2 PCR testing, and date of full vaccination.
Both vaccines were highly effective during this study period against SARS-CoV-2
infection
mRNA-1273: 86%, 95%CI: 81-90.6%;
BNT162b2: 76%, 95%CI: 69-81%
and COVID-19 associated hospitalization
mRNA-1273: 91.6%, 95% CI: 81-97%;
BNT162b2: 85%, 95% CI: 73-93%.
However, in July, the effectiveness against
infection was considerably lower for
mRNA-1273 76%, 95% CI: 58-87% [and] more pronounced [reduced effectivenss for]
BNT162b2 42%, 95% CI: 13-62%.
[This was during] ... Delta variant prevalence in Minnesota increase from 0.7% in May to over 70% in July whereas the Alpha variant prevalence decreased from 85% to 13% over the same time period.
I was looking thru the paper for the effectivenss of the vaccines against Delta hospitalizations but couldn't find it offhand, I was in too much of a hurry to head out shopping after a busy morning. and then had to fix dinner when I got home.
I've been posting 40% effectiveness against Delta infection for quite some time now, based on the Israeli study (which extensively used Pfizer). If the stats are the same, it's an 80% reduction in Delta hospitalizations. I'm sure the figures are buried in there somewhere.
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Pity would be no more,
If we did not MAKE men poor - William Blake
THUGR posts about Putin so much, he must be in love.
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They'll just keep making up fake numbers until you stop taking them seriously.
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Vaccinated People: "You need to get muh vaccination shots that don't work because I got muh vaccination shots that don't work and I'm afraid of people that didn't get muh vaccination shots that don't work because muh vaccination shots that don't work don't work."
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Ah, I found the info in a graph: Protection against (primarily) Delta hospitalizations/ICU admissions was approx 80% for Moderna and 75% for Pfizer/BNT in July in Minnesota. No deaths were recorded in either cohort in Minnesota during the study. When the study was expanded to all states with Mayo facilities/patients, there was one death associated with Moderna and none with Pfizer/BNT.
Since there were at least 36,000 matched-patients in each cohort (unvax, Moderna, Pfizer/BNT) I think this is a robust study.
For people who like tabular data: Moderna v Pfizer/BNT v unvax
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Pity would be no more,
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Quote:
Other variants trigger more traditional COVID-19 symptoms that resemble the flu, such as the loss of smell, fever, shortness of breath, or persistent cough. However, the Delta variant appears to present more like the common cold, causing upper respiratory symptoms such as a sore throat or runny nose.
https://www.verywellhealth.com/delta-variant-covid-different-symptoms-
5191950
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Pity would be no more,
If we did not MAKE men poor - William Blake
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NYTimes
United States ›
Avg. on Aug. 5 14-day change
New cases 100,199 +119% cases trajectory last two weeks
New deaths 439 +74% deaths trajectory last two weeks
United States ›
Avg. on Aug. 7 14-day change
New cases 108,513 +111% cases trajectory last two weeks
New deaths 506 +89% deaths trajectory last two weeks
United States ›
Avg. on Aug. 8 14-day change
New cases 110,360 +112% cases trajectory last two weeks
New deaths 516 +92% deaths trajectory last two weeks
United States ›
Avg. on Aug. 10 14-day change
New cases 118,067 +86% cases trajectory last two weeks
New deaths 608 +102% deaths trajectory last two weeks
United States ›
Avg. on Aug. 12 14-day change
New cases 125,894 +76% cases trajectory last two weeks
New deaths 616 +92% deaths trajectory last two weeks
It looks like the peak is passing. Proportionally, there doesn't seem to have been a delta 'youth benefit' when it comes to deaths, perhaps because POC were also heavily represented among the unvaxed.
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Quote:I'll have to go back to my source that says they weren't, and put it on my watch list. It'll take some digging.
Originally posted by SIGNYM:
OK, this is the first that I've heard that these are both full-length spike protein-encoding vaccines. I had read that sputnik V was, but didn't know that about these
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So I've been digging into the claim that the S1 subunit of the SARS-CoV-2 spike protein (the one that binds to ACE2 receptors) is toxic in itself, and that being exposed to the S1 subunit through vaccination causes COVID-19-like disease.
And I dug through all the literature to see for myself.
The end result is - that claim is almost completely not likely to be true.
And I was all set to start posting. But then I found this, which summarizes the topic nicely. So rather than type endless amounts, I'll just link it: https://sciencebasedmedicine.org/the-deadly-coronavirus-spike-protein/
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This is something to keep an eye on.
The paper indicates that while the spike protein is subject to mutation, there's a highly conserved region of the entire spike protein (both S1 and S2 units) where they link together. This highly conserved region is not only highly conserved between SARS(1) and SARS(2) ... but conserved between many different versions of human and animal coronavirus.
If this protein portion triggers neutralizing antibodies, it could be a far superior vaccine.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151553/
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NYTimes
United States ›
Avg. on Aug. 5 14-day change
New cases 100,199 +119% cases trajectory last two weeks
New deaths 439 +74% deaths trajectory last two weeks
United States ›
Avg. on Aug. 7 14-day change
New cases 108,513 +111% cases trajectory last two weeks
New deaths 506 +89% deaths trajectory last two weeks
United States ›
Avg. on Aug. 8 14-day change
New cases 110,360 +112% cases trajectory last two weeks
New deaths 516 +92% deaths trajectory last two weeks
United States ›
Avg. on Aug. 10 14-day change
New cases 118,067 +86% cases trajectory last two weeks
New deaths 608 +102% deaths trajectory last two weeks
United States ›
Avg. on Aug. 12 14-day change
New cases 125,894 +76% cases trajectory last two weeks
New deaths 616 +92% deaths trajectory last two weeks
United States ›
Avg. on Aug. 13 14-day change
New cases 128,537 +66% cases trajectory last two weeks
New deaths 651 +116% deaths trajectory last two weeks
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