Hydroxychloriquine, The Cure For Wuhan Coronavirus (Fauci Flu)
POSTED BY: JEWELSTAITEFAN
UPDATED: Tuesday, December 31, 2024 14:31
VIEWED: 11571
PAGE 3 of 13
https://en.wikipedia.org/wiki/Evidence-based_medicine
Evidence-based guidelines and policies
Main article: Medical guideline
David M. Eddy first began to use the term "evidence-based" in 1987 in workshops and a manual commissioned by the Council of Medical Specialty Societies to teach formal methods for designing clinical practice guidelines. The manual was eventually published by the American College of Physicians.[22][23] Eddy first published the term "evidence-based" in March, 1990 in an article in the Journal of the American Medical Association that laid out the principles of evidence-based guidelines and population-level policies, which Eddy described as "explicitly describing the available evidence that pertains to a policy and tying the policy to evidence instead of standard-of-care practices or the beliefs of experts. The pertinent evidence must be identified, described, and analyzed. The policymakers must determine whether the policy is justified by the evidence. A rationale must be written."[24] He discussed "evidence-based" policies in several other papers published in JAMA in the spring of 1990.[24][25] Those papers were part of a series of 28 published in JAMA between 1990 and 1997 on formal methods for designing population-level guidelines and policies.[26]
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Here is the pulse-ox post from 21 April:
Quote:
Originally posted by second:
Here’s a Lifesaving COVID-19 Test That Costs Almost Nothing
Well, almost nothing after you buy the $40 pulse/oxygen meter from Walgreens. It is next to blood pressure monitors and blood glucose monitors.
www.motherjones.com/kevin-drum/2020/04/heres-a-lifesaving-covid-19-tes
t-that-costs-almost-nothing/
The New York Times ran a fascinating op-ed on Monday, and I’m surprised that it hasn’t gotten more attention. Here’s the nickel summary: a hotshot ER doctor volunteered to spend time at Bellevue Hospital in Manhattan and discovered something odd. Practically everyone he saw had pneumonia caused by COVID-19:
Even patients without respiratory complaints had Covid pneumonia. The patient stabbed in the shoulder, whom we X-rayed because we worried he had a collapsed lung, actually had Covid pneumonia. In patients on whom we did CT scans because they were injured in falls, we coincidentally found Covid pneumonia. Elderly patients who had passed out for unknown reasons and a number of diabetic patients were found to have it.
And here is what really surprised us: These patients did not report any sensation of breathing problems, even though their chest X-rays showed diffuse pneumonia and their oxygen was below normal. How could this be?
www.nytimes.com/2020/04/20/opinion/coronavirus-testing-pneumonia.html
You can—and should!—click the link to read the details, but the short answer turns out to be that COVID-19 attacks the lungs in an unusual way: it causes the air sacs to collapse and oxygen levels to fall, but the lungs still expel carbon dioxide normally. Since it’s carbon dioxide buildup that causes you to feel short of breath, patients had never even noticed anything was wrong:
A vast majority of Covid pneumonia patients I met had remarkably low oxygen saturations at triage — seemingly incompatible with life — but they were using their cellphones as we put them on monitors….Patients compensate for the low oxygen in their blood by breathing faster and deeper — and this happens without their realizing it….By the time patients have noticeable trouble breathing and present to the hospital with dangerously low oxygen levels, many will ultimately require a ventilator.
As you know, about 80 percent of people with COVID-19 have either mild symptoms or no symptoms. But the other 20 percent develop pneumonia and many end up on ventilators and eventually die. The problem is that they don’t feel anything for the first week, and by the time they do it’s too late. So how can we catch these cases earlier? With this:
This is a pulse oximeter, and it measures the level of oxygenation in your blood. You probably get a quick oxygenation test every time you see a doctor. So the answer is: test your blood oxygenation every day. If it falls below normal levels, get to an ER and get tested for COVID-19. Your chances of survival are way higher if you can get to it early.
Yes, I Bought a Pulse Oximeter Today
by Kevin Drum
Just to follow up on this morning’s post, I did indeed go out to Walgreens and buy a pulse oximeter today.
www.motherjones.com/kevin-drum/2020/04/yes-i-bought-a-pulse-oximeter-t
oday/
Quote:
The Joss Whedon script for Serenity, where Wash lives, is Serenity-190pages.pdf at www.mediafire.com/folder/1uwh75oa407q8/Firefly
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Copied from the main thread, from 8 April:
Quote:
Originally posted by SIGNYM:
And FINALLY!!!
Blue shop towels filter small particles better than cotton!Quote:
Using blue shop towels in homemade face masks can filter particles 2x to 3x better than cotton, 3 clothing designers discover after testing dozens of fabrics
..."We spent a few days researching and brainstorming any material that could filter: coffee filters, batting, window shades, Swiffer, interfacing, etc., all the way to more technical materials that are available to specialized industrial sectors like aviation, oil refinery, medical fields," Schempf said.
They bought a $1,400 particulate-counter device from Grainger that measures filtration ability down to 0.3 microns and spent another 10 sleepless days testing all the fabrics they could find.
They wanted a material they could buy as easily as cotton but that balanced filtration with breathability — they discovered that HEPA vacuum-cleaner bags, for instance, had great filtration but were too suffocating to wear.
The ideal material turned out to be stretchy blue shop towels made from a polyester hydro knit.
Inserting two of these towels into an ordinary cotton mask brought filtration up to 93% of particles as small as 0.3 microns, the smallest their machine could test. Meanwhile, the cotton masks filtered 60% of particles at best in their tests, Schempf said.
Polyester hydro knit towels are readily available at hardware and automotive stores. The two brands they tested were ToolBox's shop towel and ZEP's industrial blue towel. Interestingly, Scott's pro shop towels, which are also made with a hydro knit fabric, didn't work as well, Schempf said.
https://www.businessinsider.com/homemade-mask-using-hydro-knit-shop-to
wel-filters-better-2020-4?op=1
Thanks to hubby for finding this!
-----------
Pity would be no more,
If we did not MAKE men poor - William Blake
#STAYTHEFUCKHOME
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From the other thread:
From 23 April:
Quote:One of the problems with chloroquine (related to HCQ) is that it causes significant - and sometimes fatal - heart arrhythmias. Both these drugs have been used for a long time to treat other conditions besides malaria, such as lupus, As such, their side effects are well known. After a debate about the relative safety of both drugs, a small study in Brazil was launched to test chloroquine, as it was deemed the safer drug. The study was halted after only 10 days due to a large number of deaths (~17% of patients) on the higher dose. https://www.medrxiv.org/content/10.1101/2020.04.07.20056424v2
Originally posted by 1KIKI:Quote:
Originally posted by SIGNYM:
... having heard very similar things about hydroxychloroquine (HCQ) ...
kiki does not really endorse the fake Trial in Brazil, but posts of it here. The purpose of the Fake Trial was to discredit HCQ/CQ since it had already proven reliable for about 80 years. It has already been known that at higher doses it causes problems with hearts, so the Fake Trial intentionally gave higher doses in order to have pretext to halt the Fake Trial.
This is a similar tactic used in prior Fake Trials which were manipulated to fail.
One was the Hydrazine Sulfate cancer cure which the NIH pretended to run in the 1990s. The one thing that everybody knew could not be done is consume peanuts or peanut butter while taking Hydrazine Sulfate. After almost all of the Trial subjects were showing regression and absence of their cancers, in order to Fail the Trial, the NIH directed that all of the recovering patients switch their diets from "no peanuts" to requiring them to all consume peanuts every meal. Therefore, obviously, these patients died, giving pretext for the excuse to cancel the Fake Trials and declare the treatment ineffective.
Seems like the same thing now with the Fake Trials for HCQ. Anything for Doctors to kill off some more patients and Big Pharma to make more $$$.
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There have been, still are, and will be, many, MANY trials of CQ/ HCQ in many countries and also conducted by international bodies.
This link to a database - using COVID-19 as the broadest possible search terms across the globe - came up with 2,834 listed studies of all kinds on COVID-19. These are the ones that have reached some kind of end that involve various forms of chloroquine.
Of the ones that were concluded, and that have published results, all cite either lack of benefit, or high-mortality side effects.
https://clinicaltrials.gov/ct2/show/study/NCT04343768?cond=COVID-19&am
p;draw=4&rank=126
Shahid Beheshti University of Medical Sciences
Completed
no results published
https://clinicaltrials.gov/ct2/show/study/NCT04491994?cond=COVID-19&am
p;draw=13&rank=1076
UNICEF
Completed
no results published
https://clinicaltrials.gov/ct2/show/NCT04261517?cond=COVID-19&draw
=13&rank=1042
Shanghai Public Health Clinical Center
Completed / A pilot study of hydroxychloroquine in treatment of patients with moderate COVID-19
https://pubmed.ncbi.nlm.nih.gov/32391667/
http://www.zjujournals.com/med/CN/10.3785/j.issn.1008-9292.2020.03.03
no difference from control
https://clinicaltrials.gov/ct2/show/NCT04341870?cond=COVID-19&draw
=13&rank=1028
Study of Immune Modulatory Drugs and Other Treatments in COVID-19 Patients: Sarilumab, Azithromycin, Hydroxychloroquine Trial - CORIMUNO-19 - VIRO (CORIMUNO-VIRO)
Assistance Publique - Hôpitaux de Paris
Suspended (DSMB recommendation (futility))
https://clinicaltrials.gov/ct2/show/NCT04348474?cond=COVID-19&draw
=12&rank=918
Efficacy and Safety of Hydroxychloroquine and Azithromycin for the Treatment of Ambulatory Patients With Mild COVID-19
Azidus Brasil
Suspended (Azidus, the CRO hired for this study by Prevent Senior has lost the interest to conduct this study.)
https://clinicaltrials.gov/ct2/show/NCT04329572?cond=COVID-19&draw
=7&rank=418
Efficacy and Safety of Hydroxychloroquine and Azithromycin for the Treatment of Hospitalized Patients With Moderate to Severe COVID-19
Azidus Brasil
Suspended (Azidus, the CRO hired for this study by Prevent Senior has lost the interest to conduct this study.)
https://clinicaltrials.gov/ct2/show/NCT04347512?cond=COVID-19&draw
=10&rank=762
EVALUATION OF THE EFFICACY OF THE HYDROXYCHLOROQUINE-AZITHROMYCIN COMBINATION IN THE IN THE PREVENTION OF COVID-19 RELATED SDRA (TEACHCOVID)
Withdrawn (In view of the notices concerning hydroxychloroquine issued by the regulatory authorities, we withdraw the protocol)
https://clinicaltrials.gov/ct2/show/NCT04358068?cond=COVID-19&draw
=9&rank=650
Evaluating the Efficacy of Hydroxychloroquine and Azithromycin to Prevent Hospitalization or Death in Persons With COVID-19
National Institute of Allergy and Infectious Diseases (NIAID) / Teva Pharmaceuticals Industries LTD
completed
No results published
https://clinicaltrials.gov/ct2/show/NCT04363203?cond=COVID-19&draw
=9&rank=623
VA Remote and Equitable Access to COVID-19 Healthcare Delivery (VA-REACH TRIAL) (VA-REACH)
Salomeh Keyhani MD / San Francisco VA Health Care System
Suspended (concerns related to study drug)
https://clinicaltrials.gov/ct2/show/NCT04371926?cond=COVID-19&draw
=6&rank=391
Prophylactic Benefit of Hydroxychloroquine in COVID-19 Cases With Mild to Moderate Symptoms and in Healthcare Workers With High Exposure Risk (PREVENT)
Texas Cardiac Arrhythmia Research Foundation
Withdrawn (Concerned about the adverse effects of HCQ)
https://clinicaltrials.gov/ct2/show/NCT04331834?cond=COVID-19&draw
=6&rank=390
Pre-Exposure Prophylaxis With Hydroxychloroquine for High-Risk Healthcare Workers During the COVID-19 Pandemic (PrEP_COVID)
Barcelona Institute for Global Health
Suspended (The study has been suspended until a new epidemic curve occurs.)
https://clinicaltrials.gov/ct2/show/NCT04323631?cond=COVID-19&draw
=6&rank=388
Hydroxychlor
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Another case taking HCQ. I think he had mentioned months ago that he would do this treatment if he got it.
https://ca.news.yahoo.com/republican-says-trump-promoted-covid-1917195
91.html
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I've noticed a lack of clarity among internet sources about dosage. Many of the Fake Trials are intentionally failing the Trial by forcing HIGH DOSES which has already been known, for many decades, to cause problems, like with the heart.
I see that the approved dosage is only for a max or 6.5mg per kg of body weight per day. For 100lbs person, this is about 290mg, or less than 150mg if taking twice per day. For 150lbs, this is about 440mg per day, or max dosage of 220mg twice per day. For 200lbs, this is about 580mg per day maximum, or 290mg twice per day.
The tablets seem to only come in 200mg size.
Successful treatment practices have indicated starting with 400mg twice on the first day, 12 hours apart, and then 200mg twice per day for 4 days. This all exceeds the approved maximum dosages as specified in the approval for use guidelines. This would certainly seem to fit the description of HIGH DOSES.
However, WHO has been trying to force Doctors to use 800mg x2 6 hours apart on the first day, followed by 400mg x2 per day for 10 days.
That certainly seems to be exceeding the maximum allowed dosage by a factor up to 11.
Many of these Fake Trials keep using the excuse of High Dose results to prematurely end their Trials and declare this inexpensive drug as dangerous.
The interwebs continue to be burying whatever information is useful bout the dosage. Perhaps more or better info is forthcoming.
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Quote:The 4 clinical trials with published results were clear about their dosing.
Originally posted by JEWELSTAITEFAN:
I've noticed a lack of clarity among internet sources about dosage.
Quote:Only 1 of 4 exclusively had high dosing, but they were following the recommendations of a Chinese study. 1 had a low-dose regimen along with a high dose regimen, the other 2 (which noted there was no difference from the control) had dosing within allowable parameters.
Many of the Fake Trials are intentionally failing the Trial by forcing HIGH DOSES which has already been known, for many decades, to cause problems, like with the heart.
Quote:There are in fact a number of very different maximum dosages DEPENDING ON USE.
I see that the approved dosage is only for a max or 6.5mg per kg of body weight per day. For 100lbs person, this is about 290mg, or less than 150mg if taking twice per day. For 150lbs, this is about 440mg per day, or max dosage of 220mg twice per day. For 200lbs, this is about 580mg per day maximum, or 290mg twice per day.
There's the maximum dosage
Usual Adult Dose for Malaria Prophylaxis
-Maximum dose: 400 mg salt (310 mg base)/dose
Usual Adult Dose for Malaria
Maximum Dose:
-First dose: 800 mg salt (620 mg base)/dose
-Second, third, and fourth dose: 400 mg salt (310 mg base)/dose
Usual Adult Dose for Systemic Lupus Erythematosus
-Doses above 400 mg/day are not recommended.
Usual Adult Dose for Rheumatoid Arthritis
Maximum dose: 600 mg salt (465 mg base)/day or 6.5 mg/kg salt (5 mg/kg base)/day, whichever is lower
https://www.drugs.com/dosage/hydroxychloroquine.html
Quote:
The tablets seem to only come in 200mg size.
Quote:There WERE no successful treatments in any of the 4 clinical trials.
Successful treatment practices
Quote:3 of 5 dosing regimens did NOT exceed the maximum doses - if you read all the dosing information!
have indicated starting with 400mg twice on the first day, 12 hours apart, and then 200mg twice per day for 4 days. This all exceeds the approved maximum dosages as specified in the approval for use guidelines. This would certainly seem to fit the description of HIGH DOSES.
Quote:That is a completely false statement. https://www.who.int/publications/m/item/informal-consultation-on-the-d
However, WHO has been trying to force Doctors to use 800mg x2 6 hours apart on the first day, followed by 400mg x2 per day for 10 days.
That certainly seems to be exceeding the maximum allowed dosage by a factor up to 11.
ose-of-chloroquine-and-hydroxychloroquine-for-the-solidarity-clinical-trial---8-april-2020 The WHO trial recommends "The Chloroquine or Hydroxychloroquine schedule selected for the trial includes two oral loading doses (250 mg per tablet CQ or 200mg per tablet HCQ), then oral twice-daily maintenance doses for ten days." For HCQ that's 400mg/day.
Quote:I know you have an agenda to make Trump right.
Many of these Fake Trials keep using the excuse of High Dose results to prematurely end their Trials and declare this inexpensive drug as dangerous.
The interwebs continue to be burying whatever information is useful bout the dosage. Perhaps more or better info is forthcoming.
But posting lies (and trying to get away with it by failing to post links) isn't the way to do it.
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If this video concerning why Hydroxychloroquine is not good to treat coronavirus doesn't answer your questions, then there's no hope for you.
T 
Stupid people don't know they're stupid, and they certainly don't realize how obvious it is to others.
Widely cited hydroxychloroquine study is ‘flawed’, Fauci tells hearing
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https://wattsupwiththat.com/2020/05/02/pseudo-science-behind-the-assau
lt-on-hydroxychloroquine/
https://www.researchgate.net/publication/331898127_Hydroxychloroquine_
usage_in_US_patients_their_experiences_of_tolerability_and_adherence_and_implications_for_treatment_Survey_results_from_3127_patients_with_SLE_conducted_by_the_Lupus_Foundation_of_A
https://vivelifecenter.com/wp-content/uploads/2020/07/White-Paper-on-H
CQ-07-22-2020.pdf
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